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1

Catch-Up Growth in Zebrafish Embryo Requires Neural Crest Cells Sustained by Irs1 Signaling

Kamei, Hiroyasu, Yoneyama, Yosuke, Hakuno, Fumihiko, Sawada, Rie, Shimizu, Toshiaki, Duan, Cunming, Takahashi, Shin-Ichiro

Journal:

Year:

2018

Language:

english

File:

PDF, 2.21 MB

english, 2018

2

Molecular mechanisms underlying the onset of degenerative aortic valve disease

Daihiko Hakuno, Naritaka Kimura, Masatoyo Yoshioka, Keiichi Fukuda

Journal:

Journal of Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 297 KB

english, 2009

3

GP4-1: Loss of PI 3-kinase-binding protein PI3KAP/XB130 suppresses thyroid function and induces enlargement of thyroid glands in mice

Yamanaka, D., Hakuno, F., Minami, S., Hashimoto, K., Suzuki, K., Chida, K., Takahashi, S.-I.

Journal:

Growth Hormone & IGF Research

Year:

2014

Language:

english

File:

PDF, 436 KB

english, 2014

4

Acetylcholinesterase (AChE) inhibition aggravates fasting-induced triglyceride accumulation in the mouse liver

Yokota, Shin-Ichi, Nakamura, Kaai, Ando, Midori, Kamei, Hiroyasu, Hakuno, Fumihiko, Takahashi, Shin-Ichiro, Shibata, Shigenobu

Journal:

Year:

2014

Language:

english

File:

PDF, 1.66 MB

english, 2014

5

Infant word segmentation recruits the cerebral network of phonological short-term memory

Minagawa, Yasuyo, Hakuno, Yoko, Kobayashi, Ai, Naoi, Nozomi, Kojima, Shozo

Journal:

Brain and Language

Year:

2017

Language:

english

File:

PDF, 1.26 MB

english, 2017

6

Social interaction facilitates word learning in preverbal infants: Word–object mapping and word segmentation

Hakuno, Yoko, Omori, Takahide, Yamamoto, Jun-ichi, Minagawa, Yasuyo

Journal:

Infant Behavior and Development

Year:

2017

Language:

english

File:

PDF, 909 KB

english, 2017

7

DYNAMIC DESTRUCTION EXPERIMENT WITH MASONRY ARCH MODELS

KONNO, Yoshisato, HAKUNO, Motohiko, AITANI, Takeshi, TAKADA, Nobuyuki

Journal:

Proceedings of the Japan Society of Civil Engineers

Year:

1983

File:

PDF, 12.55 MB

1983

8

OBSERVATION OF EARTHQUAKES ON AN ARCH DAM AND ITS ABUTMENT

Okamoto, Shunzo, Hakuno, Motohiko, Kato, Katsuyuki, Otawa, Michiko

Journal:

Transactions of the Japan Society of Civil Engineers

Year:

1964

File:

PDF, 3.54 MB

1964

9

OBSERVATION OF EARTHQUAKES ON AN ARCH DAM

Okamoto, Shunzo, Kato, Katsuyuki, Hakuno, Motohiko, Miyakoshi, Yoshiteru

Journal:

Transactions of the Japan Society of Civil Engineers

Year:

1961

File:

PDF, 3.68 MB

1961

10

Armored Heart Because of Tuberculous Constrictive Pericarditis

Uchi, Takafumi, Hakuno, Daihiko, Fukae, Tomoaki, Takahashi, Masashi, Takiguchi, Shunichi, Li, Hui-Chong, Nishizawa, Kenya, Nozaki, Hiroyuki, Sueyoshi, Koichiro

Journal:

Circulation Cardiovascular Imaging

Year:

2019

Language:

english

File:

PDF, 191 KB

english, 2019

11

Stromal Cells in the Pathogenesis of Inflammatory Bowel Disease

Barnhoorn, M C, Hakuno, S K, Bruckner, R S, Rogler, G, Hawinkels, L J A C, Scharl, M

Journal:

Journal of Crohn's and Colitis

Year:

2020

Language:

english

File:

PDF, 2.72 MB

english, 2020

12

Interactive live fNIRS reveals engagement of the temporoparietal junction in response to social contingency in infants

Hakuno, Yoko, Hata, Masahiro, Naoi, Nozomi, Hoshino, Ei-ichi, Minagawa, Yasuyo

Journal:

Year:

2020

File:

PDF, 7.77 MB

2020

13

Distinct element analysis for rock avalanche : Struct Engng Earthq Engng V6, N1, April 1989, P131s–140s

L. Casaverde, K. Iwashita, Y. Tarumi, M. Hakuno

Journal:

International Journal of Rock Mechanics and Mining Sciences & Geomechanics Abstracts

Year:

1990

Language:

english

File:

PDF, 234 KB

english, 1990

14

Upregulation of P-cadherin expression in the lesional skin of pemphigus, Hailey-Hailey disease and Darier’s disease

Megumi Hakuno, Masashi Akiyama, Hiroshi Shimizu, Margaret J. Wheelock, Takeji Nishikawa

Journal:

Journal of Cutaneous Pathology

Year:

2001

Language:

english

File:

PDF, 117 KB

english, 2001

15

Dissociation of intra- and extracellular domainsof desmosomal cadherins and E-cadherin inHailey–Hailey disease and Darier’s disease

M. Hakuno, H. Shimizu, M. Akiyama, M. Amagai, J.K. Wahl, M.J. Wheelock, T. Nishikawa

Journal:

British Journal of Dermatology

Year:

2000

Language:

english

File:

PDF, 658 KB

english, 2000

16

The Schizosaccharomyces pombe mra1 gene, which is required for cell growth and mating, can suppress the mating inefficiency caused by a deficit in the Ras1 activity

Fumihiko Hakuno, David A. Hughes, Masayuki Yamamoto

Journal:

Year:

1996

Language:

english

File:

PDF, 1.17 MB

english, 1996

17

The effect of carbon tetrachloride on liver and plasma lipids, activities of lipases and fatty acids syntheses in rats

K. Kanzaki, T. Kagiyama, A. Hayakawa, J. Kinoshita, J. Mori, T. Hakuno

Journal:

Journal of Gastroenterology

Year:

1970

Language:

english

File:

PDF, 68 KB

english, 1970

18

Estimates of Australia antigen carrier rate in Nagasaki area populations

K. Matsunaga, H. Nishida, T. Takahashi, I. Mori, T. Hakuno, N. Nakaguchi, T. Aramaki, K. Kanzaki, A. Hayakawa, S. Osazima

Journal:

Journal of Gastroenterology

Year:

1972

Language:

english

File:

PDF, 68 KB

english, 1972

19

Evaluation of liver function tests in primary carcinoma of the liver

S. Osajima, Y. Ikeda, T. Kajiyama, K. Kanzaki, K. Futatsuki, Y. Yamaguchi, I. Mori, T. Hakuno

Journal:

Journal of Gastroenterology

Year:

1969

Language:

english

File:

PDF, 76 KB

english, 1969

20

Measurement of dna content per nucleus of mucosal cells from various gastric lesions

Y. Ikeda, T. Kajiyama, K. Kanzaki, I. Kinoshita, K. Futatuki, H. Hirayama, Y. Yamaguti, T. Hakuno, I. Mori

Journal:

Journal of Gastroenterology

Year:

1969

Language:

english

File:

PDF, 58 KB

english, 1969

21

Langerhans cells in the lymph node: mirror section and immunoelectron microscopic studies

Mikihiro Shamoto, Masanori Shinzato, Satoru Hosokawa, Chiyuki Kaneko, Takashi Hakuno, Kazutaka Nomoto

Journal:

Virchows Archiv B Cell Pathology Zell-pathologie

Year:

1992

Language:

english

File:

PDF, 4.10 MB

english, 1992

22

Actin-related defense mechanism to reject penetration attempt by a non-pathogen is maintained in tobacco BY-2 cells

Issei Kobayashi, Humiaki Hakuno

Journal:

Year:

2003

Language:

english

File:

PDF, 288 KB

english, 2003

23

Application of mesenchymal stem cell-derived cardiomyocytes as bio-pacemakers: current status and problems to be solved

Yuichi Tomita, Shinji Makino, Daihiko Hakuno, Naoichiro Hattan, Kensuke Kimura, Shunichiro Miyoshi, Mitsushige Murata, Masaki Ieda, Keiichi Fukuda

Journal:

Medical and Biological Engineering and Computing

Year:

2007

Language:

english

File:

PDF, 558 KB

english, 2007

24

Role of Angiogenetic Factors in Cardiac Valve Homeostasis and Disease

Daihiko Hakuno, Naritaka Kimura, Masatoyo Yoshioka, Keiichi Fukuda

Journal:

Journal of Cardiovascular Translational Research

Year:

2011

Language:

english

File:

PDF, 1.48 MB

english, 2011

25

Association between β-adrenoceptor gene polymorphisms and relative response to β2-agonists and anticholinergic drugs in Japanese asthmatic patients

Koichiro ASANO, Wakako YAMADA-YAMASAWA, Hiroyasu KUDOH, Tatsu MATSUZAKI, Takahiro NAKAJIMA, Haruhiko HAKUNO, Rika HIRAOKA, Koichi FUKUNAGA, Tsuyoshi OGUMA, Koichi SAYAMA, Kazuhiro YAMAGUCHI, Akira NAG

Journal:

Year:

2010

Language:

english

File:

PDF, 191 KB

english, 2010

26

KIBRA Suppresses Apical Exocytosis through Inhibition of aPKC Kinase Activity in Epithelial Cells

Yohei Yoshihama, Kazunori Sasaki, Yosuke Horikoshi, Atsushi Suzuki, Takashi Ohtsuka, Fumihiko Hakuno, Shin-Ichiro Takahashi, Shigeo Ohno, Kazuhiro Chida

Journal:

Current Biology

Year:

2011

Language:

english

File:

PDF, 1.40 MB

english, 2011

27

Morphological analysis of developmental changes in pontine noradrenergic neuronal groups in the neonatal rat

Yoko Ito, Yoshitaka Oyamada, Haruhiko Hakuno, Kazuhiro Yamaguchi

Journal:

Year:

2002

Language:

english

File:

PDF, 181 KB

english, 2002

28

Erratum to: Morphological analysis of developmental changes in pontine noradrenergic neuronal groups in the neonatal rat: [Brain Res. 925 (2002) 107–109]

Yoko Ito, Yoshitaka Oyamada, Haruhiko Hakuno, Kazuhiro Yamaguchi

Journal:

Year:

2002

File:

PDF, 118 KB

2002

29

Novel missense mutation in the IGF-I receptor L2 domain results in intrauterine and postnatal growth retardation

Yuki Kawashima, Katsumi Higaki, Toshiaki Fukushima, Fumihiko Hakuno, Jun-ichi Nagaishi, Keiichi Hanaki, Eiji Nanba, Shin-Ichiro Takahashi, Susumu Kanzaki

Journal:

Clinical Endocrinology

Year:

2012

Language:

english

File:

PDF, 390 KB

english, 2012

30

AN AUTOPSY CASE OF ALKAPTONURIA WITH OCHRONOSIS

Issei Nishimori, Junichi Itoh, Tohru Hakuno

Journal:

Pathology International

Year:

1970

Language:

english

File:

PDF, 534 KB

english, 1970

31

Autocrine/Paracrine Secretion of IL-6 Family Cytokines Causes Angiotensin II-Induced Delayed STAT3 Activation

Motoaki Sano, Keiichi Fukuda, Hiroaki Kodama, Toshiyuki Takahashi, Takahiro Kato, Daihiko Hakuno, Toshihiko Sato, Tomohiro Manabe, Satoko Tahara, Satoshi Ogawa

Journal:

Biochemical and Biophysical Research Communications

Year:

2000

Language:

english

File:

PDF, 113 KB

english, 2000

32

Role of EGF Receptor and Pyk2 in Endothelin-1-induced ERK Activation in Rat Cardiomyocytes

Hiroaki Kodama, Keiichi Fukuda, Toshiyuki Takahashi, Motoaki Sano, Takahiro Kato, Satoko Tahara, Daihiko Hakuno, Toshihiko Sato, Tomohiro Manabe, Fusako Konishi, Satoshi Ogawa

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2002

Language:

english

File:

PDF, 366 KB

english, 2002

33

Common marmoset embryonic stem cell can differentiate into cardiomyocytes

Hao Chen, Fumiyuki Hattori, Mitsushige Murata, Weizhen Li, Shinsuke Yuasa, Takeshi Onizuka, Kenichiro Shimoji, Yohei Ohno, Erika Sasaki, Kensuke Kimura, Daihiko Hakuno, Motoaki Sano, Shinji Makino, Sa

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 1.49 MB

english, 2008

34

Differential subcellular localization of insulin receptor substrates depends on C-terminal regions and importin β

Tomohiro Kabuta, Kazumi Take, Chihana Kabuta, Fumihiko Hakuno, Shin-Ichiro Takahashi

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 469 KB

english, 2008

35

Insulin receptor substrate-3, interacting with Bcl-3, enhances p50 NF-κB activity

Tomohiro Kabuta, Fumihiko Hakuno, Yoshitake Cho, Daisuke Yamanaka, Kazuhiro Chida, Tomoichiro Asano, Keiji Wada, Shin-Ichiro Takahashi

Journal:

Biochemical and Biophysical Research Communications

Year:

2010

Language:

english

File:

PDF, 1.22 MB

english, 2010

36

Insulin/insulin-like growth factor (IGF) stimulation abrogates an association between a deubiquitinating enzyme USP7 and insulin receptor substrates (IRSs) followed by proteasomal degradation of IRSs

Hidehito Yoshihara, Toshiaki Fukushima, Fumihiko Hakuno, Yasushi Saeki, Keiji Tanaka, Akihiro Ito, Minoru Yoshida, Shun-ichiro Iemura, Tohru Natsume, Tomoichiro Asano, Kazuhiro Chida, Leonard Girnita,

Journal:

Biochemical and Biophysical Research Communications

Year:

2012

Language:

english

File:

PDF, 471 KB

english, 2012

37

The anti-angiogenic factor, Tenomodulin, has a pivotal role in chordae tendineae cordis

Naritaka Kimura, Daihiko Hakuno, Chisa Syukunami, Yuji Hiraki, Ryohei Yozu, Keiichi Fukuda

Journal:

Journal of Cardiac Failure

Year:

2008

Language:

english

File:

PDF, 47 KB

english, 2008

38

A Potent Angiogenic Factor Periostin Accelerates Degeneration of the Cardiac Valves

Daihiko Hakuno, Naritaka Kimura, Masatoyo Yoshioka, Akira Kudou, Yasunori Okada, Ryohei Yozu, Satoshi Ogawa, Keiichi Fukuda

Journal:

Journal of Cardiac Failure

Year:

2008

Language:

english

File:

PDF, 50 KB

english, 2008

39

Identification of Bombyx mori Akt and its phosphorylation by bombyxin stimulation

Shinji Nagata, Fumihiko Hakuno, Shin-Ichiro Takahashi, Hiromichi Nagasawa

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Year:

2008

Language:

english

File:

PDF, 1.17 MB

english, 2008

40

Enhanced oxidative stress in GH-transgenic rat and acromegaly in humans

Hitoshi Nishizawa, Anastasia-Evi Handayaningsih, Genzo Iguchi, Yoshitake Cho, Michiko Takahashi, Masaaki Yamamoto, Kentaro Suda, Kohei Kasahara, Fumihiko Hakuno, Keitaro Yamanouchi, Masugi Nishihara,

Journal:

Growth Hormone & IGF Research

Year:

2012

Language:

english

File:

PDF, 633 KB

english, 2012

41

HSP90 interacting with IRS-2 is involved in cAMP-dependent potentiation of IGF-I signals in FRTL-5 cells

Toshiaki Fukushima, Hiroshi Okajima, Daisuke Yamanaka, Miyako Ariga, Shinji Nagata, Akihiro Ito, Minoru Yoshida, Tomoichiro Asano, Kazuhiro Chida, Fumihiko Hakuno, Shin-Ichiro Takahashi

Journal:

Molecular and Cellular Endocrinology

Year:

2011

Language:

english

File:

PDF, 615 KB

english, 2011

42

Optical mapping of pontine chemosensitive regions of neonatal rat

Yoko Ito, Yoshitaka Oyamada, Yasumasa Okada, Haruhiko Hakuno, Ryoma Aoyama, Kazuhiro Yamaguchi

Journal:

Neuroscience Letters

Year:

2004

Language:

english

File:

PDF, 161 KB

english, 2004

43

Effects of inactivation and stimulation of locus coeruleus on respiratory activity of neonatal rat

Haruhiko Hakuno, Yoshitaka Oyamada, Michie Murai, Yoko Ito, Kazuhiro Yamaguchi

Journal:

Respiratory Physiology & Neurobiology

Year:

2004

Language:

english

File:

PDF, 207 KB

english, 2004

44

Role of Kir2.2 in hypercapnic ventilatory response during postnatal development of mouse

Yoshitaka Oyamada, Kazuhiro Yamaguchi, Michie Murai, Haruhiko Hakuno, Akitoshi Ishizaka

Journal:

Respiratory Physiology & Neurobiology

Year:

2005

Language:

english

File:

PDF, 158 KB

english, 2005

45

The Potent Angiogenic Factor Periostin Accelerates Degeneration and Sclerosis of the Cardiac Valve Complex

Daihiko Hakuno, Naritaka Kimura, Tokuhiro Kimura, Yasunori Okada, Ryohei Yozu, Satoshi Ogawa, Keiichi Fukuda, Akira Kudo

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2008

Language:

english

File:

PDF, 44 KB

english, 2008

46

Chordae tendineae cordis are covered and protected by the anti-angiogenic factor, Tenomodulin

Naritaka Kimura, Daihiko Hakuno, Ryohei Yozu, Keiichi Fukuda

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2008

Language:

english

File:

PDF, 49 KB

english, 2008

47

Long-term hormonal regulation of the cAMP-specific phosphodiesterases in cultured FRTL-5 thyroid cells

Shin-Ichiro Takahashi, Taku Nedachi, Toshiaki Fukushima, Kota Umesaki, Yoshiaki Ito, Fumihiko Hakuno, Judson J Van Wyk, Marco Conti

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2001

Language:

english

File:

PDF, 472 KB

english, 2001

48

Microbial contamination of ‘sterile water’ used in Japanese hospitals

S. Oie, M. Oomaki, K. Yorioka, T. Tatsumi, M. Amasaki, T. Fukuda, H. Hakuno, K. Nagano, M. Matsuda, N. Hirata, N. Miyano, A. Kamiya

Journal:

Journal of Hospital Infection

Year:

1998

Language:

english

File:

PDF, 785 KB

english, 1998

49

OR03-1 Nedd4 ASSOCIATES WITH INSULIN RECEPTOR SUBSTRATES (IRSs) LEADING TO ENHANCEMENT OF IGF SIGNALS WITH ITS UBIQUITIN LIGASE ACTIVITY

Toshiaki Fukushima, Fumihiko Hakuno, Shinji Nagata, Shin-Ichiro Takahashi

Journal:

Growth Hormone & IGF Research

Year:

2006

Language:

english

File:

PDF, 61 KB

english, 2006

50

OR13-1 GH IMPAIRS INSULIN-DEPENDENT PI 3-KINASE ACTIVITY BOUND TO IRS-2 LEADING TO INHIBITION OF GLUT4 ACTIVITY IN 3T3-L1 ADIPOCYTES

Kiyoshi Arai, Naoko Suzuki, Tomomi Ogata, Michihiro Shibata, Tomoichiro Asano, Fumihiko Hakuno, Shin-Ichiro Takahashi

Journal:

Growth Hormone & IGF Research

Year:

2006

Language:

english

File:

PDF, 79 KB

english, 2006

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